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Spirometric assessment of pulmonary function in road-side vendors : a pilot study

机译:肺功能检查法对路边摊贩肺功能的评估:一项初步研究

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摘要

Although much is known about the chronic effects of air pollution on pulmonary function, short-term changes in response to pollution levels over days, weeks and months have been less well documented. Such investigation requires field studies using portable equipment. Therefore, we studied forced vital capacity (FVC), forced expiratory volume in 1 second, and peak expiratory flow rate using a conventional hand-held spirometer, in a sample of Hong Kong roadside vendors (n = 21; age, 48.7 ± 13.4 yr) across 2 days (n = 14), 4 weeks (n = 10), and 3 months (n = 7). In addition, exhaled carbon monoxide was measured, and percent carboxyhemoglobin derived. There was no difference in pulmonary function between a weekday and the weekend. Only FVC decreased over 4 weeks and 3 months compared with initial testing, but this was not associated with pollution level. Our results support that the technology of hand-held spirometry needs to be advanced to detect potential short-term changes in the real world context, in pulmonary function including small airway reactivity and airway closure. Future generations of this technology need to provide the capacity for more detailed spirometry suitable for field studies.
机译:尽管人们对空气污染对肺功能的慢性影响知之甚少,但是关于污染水平在几天,几周和几个月内发生的短期变化的文献报道却很少。这种调查需要使用便携式设备进行现场研究。因此,我们在香港路边摊贩样本中(n = 21;年龄为48.7±13.4岁),使用传统的手持式肺活量计研究了强制肺活量(FVC),1秒内的强制呼气量和最大呼气流速。 )跨2天(n = 14),4周(n = 10)和3个月(n = 7)。另外,测量呼出的一氧化碳,并衍生出羧基血红蛋白百分比。在工作日和周末之间,肺功能无差异。与最初的测试相比,只有FVC在4周和3个月内下降,但这与污染水平无关。我们的结果表明,需要改进手持式肺活量测定技术,以检测现实世界中潜在的短期变化,包括肺功能(包括小气道反应性和气道闭合)的短期变化。这项技术的后代需要提供适用于现场研究的更详细的肺活量测定技术的能力。

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